Jason Umans

Jason Umans, MD, PhD, is scientific director of the basic and translational science laboratories at MedStar Health Research Institute (MHRI).

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He is the program director for Research Education, Training and Career Development at the Georgetown-Howard Universities Center for Clinical and Translational Science and also associate director of its General Clinical Research Center. In addition, he is an associate professor of medicine and obstetrics/gynecology at Georgetown University.

As an experienced clinical investigator, Dr. Umans is committed to multidisciplinary team science. As director of the basic and translational laboratories at MHRI, he has primary responsibility for sample acquisition, processing, transport, storage, and assay procedures for several large NIH-supported observational studies and clinical trials. These responsibilities include overseeing the design of complex multisite sample collection, processing and transport protocols; training and supervising field and laboratory staff; coordinating activities with multidisciplinary, geographically dispersed study teams; and providing rigorous quality control. Dr. Umans has expertise in developing, validating, and adapting new assays using multiple laboratory techniques and instrument platforms.

His research background includes experience as a principal investigator of a genetic epidemiology study, as a co-investigator for several observational studies and clinical trials, as a co-principal investigator in a clinical trials network, and as a clinical pharmacologist and nephrologist. He is the program director of the MedStar Research Scholars Program, and he serves on the Scientific Advisory Board at MHRI. His research is currently focused on mechanisms contributing to cardiovascular disease and health disparities in minority and underserved populations.

Dr. Umans, an American Society of Hypertension (ASH) specialist in clinical hypertension, is board-certified in internal medicine, nephrology, and clinical pharmacology. He is internationally recognized as an expert in medical disorders during pregnancy, particularly hypertension and kidney disease. Along with colleagues at MedStar Washington Hospital Center and MedStar Georgetown, he leads the NIH-supported Obstetric-Fetal Pharmacology Research Unit.

He has published more than 150 peer-reviewed articles, on topics including vascular biology, pharmacokinetic modeling, drug assay development, obstetric and fetal pharmacology, neuropharmacology, vascular and renal physiology, hemodynamic regulation, inflammatory mechanisms, diabetes, kidney disease and health disparities. He also has written book chapters and review articles, and has spoken widely on hypertension and renal disease in pregnancy, acute renal failure, and pharmacotherapy in pregnancy and in renal failure. He is a fellow of the American College of Physicians, and he is a member of the Society for Reproductive Investigation, the International Society for the Study of Hypertension in Pregnancy, the North American Society of Obstetric Medicine, the American Society of Nephrology, and other professional associations. In addition, he has served on two panels for the National Institute of Child Health and Human Development.

Dr. Umans received his PhD in Pharmacology and Biomathematics from Weill Cornell Graduate School of Medical Sciences. His medical degree is from Weill Cornell Medical College. He completed a residency in medicine and a fellowship in nephrology at the University of Chicago Medical Center.